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Bsense Bio Therapeutics
Sensory Neurons

About Us

Electrophysiolofical recording pipette

Bsense Bio’s approach is based on the targeting of two cation channels, a ligand-gated cation channel and a voltage-gated potassium channel, respectively, TRPV1 and Kv7.2/3, which are co-localized on sensory nociceptive neurons and are widely recognized as prominent players in the modulation of neuronal excitability. This dual activity unique approach boosts potency while providing safe and non-addictive new therapeutic potential. The company has generated preclinical proof-of-concept in several chronic pain models and Tinnitus.

Bsense Bio Therapeutics

Bsense Bio Therapeutics is developing small molecules for treating sensory hyperexcitability related disorders.

 

Bsense is pioneering a novel approach targeting multiple hyperexcitability related mechanisms using a single compound, in order to achieve greater efficacy and safety.

Electrophysiolofical recording pipette
Electrophysiolofical recording pipette

Our Team

Haim Belinson - CSO Bsense Bio

Haim Belinson, PhD.

CEO

Haim Belinson received a PhD. in neurobiology from the Tel Aviv University in Israel. Following postdoctoral training at the Department of Pediatrics, Institute for Human Genetics, UCSF, San Francisco, CA. where he studied brain development and the brain gut axis in the context of autism spectrum disorder, Dr. Belinson joined Teva pharmaceutical where he utilized broad neuroscience scientific expertise and lead pharmacology preclinical development of drugs for neurodegenerative diseases, neuropsychiatry and pain. At Teva, Dr. Belinson dealt with both the scientific aspects as well as leading various stages of drug development from ideation to PhIII. Dr. Belinson has over 15 years of experience in Neurobiology research, spanning pharmaceutical R&D, target identification/validation, behavioral pharmacology and PK/PD.

Adi Raveh - Head of Biology in Bsense Bio

Adi Raveh, PhD.

Head of Biology

A seasoned neuroscientist with expertise in drug discovery and development, possessing a Ph.D. in Biology with a specialization in ion channels biophysics and physiology from The Weizmann Institute of Science. Additionally, has conducted post-doctoral research on Alzheimer’s disease and GPCRs signaling at the Department of Biomedicine, University of Basel, Switzerland.

Board of Directors

Assaf Keret

Assaf Keret

BOD Member

Mr. Keret holds more than 15 years of financial consulting, investment banking, and project management experience. He focuses mainly on the corporate finance aspects of RMG’s Life Science practice. Prior to joining RMG, Mr. Keret worked at Swary Financial Consulting, a prominent Israeli boutique financial advisory firm, leading valuation projects for some of Israel’s largest companies. Prior to joining Swary, he worked as a financial consultant in the Deloitte Transactional Services team in Tel Aviv. Mr. Keret is a CPA, and holds an LLM, and a BA in Law and Accounting from the Interdisciplinary Center (IDC), Herzliya.
Liana Patt, PhD., MBA

Liana Patt, PhD., MBA

BOD Member

Dr. Liana Patt, Chief Executive Officer at FutuRx is a healthcare executive with over 20 years in pharma & biotech. Liana brings specific expertise in innovation evaluation, strategic development, fund raising for a wide range of technologies and therapeutic areas, through extensive value creation in NewCos establishment, development and commercialization. Before joining FutuRx Liana was the CEO of Integra Holdings, the Healthcare VC arm of the Hebrew university since 2013. Prior to that, Liana served as VP Search & Evaluation and Business Development at TEVA where she led global teams responsible for investments and in-licensing. She holds a PhD from the WIS and an MBA from Edinburgh Business School.
Leeat Bar-Eyal, PhD.

Leeat Bar-Eyal, PhD.

BOD Member

Principal at RMGP Biopharma Investment Fund, completed her PhD in the Plant and Environmental Sciences Department at the Hebrew University of Jerusalem. Leeat’s PhD research concerned desiccation tolerance mechanisms of desert crust cyanobacteria. Leeat received her BSc in biology (in the Institute of Life Science’s honors program) from the Hebrew University of Jerusalem.

Scientific Advisors

Alan D. Brown, PhD.

Alan D. Brown, PhD.

MedChem

Alan is a medicinal chemist who has worked for over 30 years in the pharma industry. He has worked across a wide range of projects and disease areas, including roles such as Exploratory and Therapeutic Area Head of Chemistry (Sexual Health, Pain, and Sensory Disorders Research Units) with Pfizer and Head of Chemistry at Benevolent AI. Alan is vastly experienced across hit generation, lead optimisation and candidate identification and has been personally involved in 20 projects which have resulted in new medicines being tested in humans. He is author/ named inventor on >80 patents and peer reviewed publications.
Jeffrey D. Kennedy, PhD.

Jeffrey D. Kennedy, PhD.

Preclinical Development

Jeffrey D. Kennedy, Ph.D. spent over 3 decades in the pharmaceutical industry working for major pharma or serving as a pharmaceutical consultant and is internationally recognized as an expert in pain pathophysiology and neuroinflammation. Following training as an immunologist and early work in the pulmonary inflammation/asthma field, Dr. Kennedy adapted this knowledge base to the neuroscience field where, as part of a 16 year career at Wyeth Research, he led pain drug discovery for Wyeth Neuroscience. He then spent 5 years at Eli Lilly and Co., where he led a behavioral pharmacology group that provided broad support to the pain and larger neuroscience therapeutic area while also serving as company representative to the EF7 IMI public-private partnership and steering committee member for the Europain consortium in addition to helping facilitate broader company partnering efforts. Since leaving pharma, Dr. Kennedy, in addition to private consulting work, has held long-term roles as grant reviewer for NINDS and as member of both NIH and FDA committees tasked with helping improve the success of pain translational R&D efforts.
Vladimir Skljarevski, M.D.

Vladimir Skljarevski, M.D.

Clinical Development

Dr. Vladimir (Vlad) Skljarevski brings more than 25 years of leadership and global neuroscience drug development experience across all phases of clinical research in academia, big pharma, and small biotech companies. As a global medical leader at Eli Lilly and Company, he designed and conducted over 20 large Phase 2 and Phase 3 trials which represented the basis for the worldwide registration of two products – Cymbalta for chronic pain, and Emgality for migraine prevention. He has an extensive regulatory, clinical operations, business development, and partnership building experience within the US, the EU, Japan, and China. More recently, he has been engaged full-time in providing consulting services for both big pharma and small biotech companies operating in the space of pain, neurodevelopmental disorders and neurodegeneration. Dr. Skljarevski holds an MD degree from the University of Sarajevo in his native Bosnia and Herzegovina (former Yugoslavia). He is a fully trained neurosurgeon with a subspecialty training in stereotactic neurosurgery from Karolinska Hospital in Stockholm, Sweden. He also completed a neurology residency at the University of Vermont in Burlington, VT, as well as a clinical fellowship in cerebrovascular diseases at the University of Ottawa in Canada. Vlad holds an active medical license in the State of Indiana and serves as a member of the US NIH external oversight committee of the HEAL (Helping to End Addiction Long-term) project.
Michael Mizhiritskii, PhD.

Michael Mizhiritskii, PhD.

CMC

Over 40 years activity in organic chemistry both in research and industry. Chief chemist of several companies. Independent adviser in organic chemistry, CMC and Medical chemistry since 2007 to companies in Israel, USA, Europe and Asia. Has played key roles in many projects for pharma, agrochemical, biotechnology, “Green chemistry” and “Biofuel” companies.

Collaborators

Inventors

Investors

Steve Davidson , PhD

Associate Professor

Prof. Bernard Attali

Prof. Bernard Attali

Inventor

Professor, Department of Physiology & Pharmacology, Sackler Faculty of Medicine, Tel Aviv University. Prof. Attali is the inventor of the technology and as such serve as a consultant to the company. Prof. Attali published over 100 research papers in leading journals in his field. In addition, he was awarded several awards, including the Israel Cancer Research Fund and the Shtacher award from the Tel-Aviv University.
Asher Peretz, PhD.

Asher Peretz, PhD.

Co-Inventor

Department of Physiology & Pharmacology, Sackler Faculty of Medicine, Tel Aviv University. Dr. Asher Peretz holds a Ph.D from the Hebrew University of Jerusalem. He is a co-inventor of the technology and will share his comprehensive knowledge and experience in the field of electrophysiology of ion channels.
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